Antagonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as inhibition of UK14304-ind...

Basic Information

ID: ALA3591123

Type: Functional

Description: Antagonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as inhibition of UK14304-induced cytoplasmic calcium mobilization at 20 uM preincubated for 15 mins by fluorometric analysis relative to control

Format: BAO_0000219

Organism: Homo sapiens

Cell type: CHO-K1

Target:  Alpha-2c adrenergic receptor(ALA1916)

Document:  ALA3588743

Antagonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as inhibition of UK14304-induced cytoplasmic calcium mobilization at 20 uM preincubated for 15 mins by fluorometric analysis relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
191.281.021.02
191.281.021.02
242.322.582.58