Basic Information
ID: ALA3591211
Type: Binding
Description: Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3591211
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 386.50 | 2.21 | 2.21 |
| 449.56 | 2.88 | 2.88 |
| 497.62 | 2.28 | 2.28 |
| 463.58 | 3.19 | 3.19 |
| 511.65 | 2.59 | 2.59 |
| 479.58 | 2.89 | 2.89 |
| 527.65 | 2.29 | 2.29 |
| 450.54 | 2.27 | 2.27 |
| 370.50 | 2.97 | 2.97 |
| 370.50 | 2.97 | 2.97 |
| 461.61 | 4.34 | 4.34 |
| 461.61 | 4.34 | 4.34 |
| 462.60 | 3.62 | 3.62 |
| 413.52 | 1.65 | 1.65 |
| 386.50 | 1.94 | 1.94 |
| 372.47 | 1.82 | 1.82 |
| 372.47 | 1.82 | 1.82 |
| 420.54 | 1.22 | 1.22 |
| 420.54 | 1.22 | 1.22 |
| 406.51 | 0.83 | 0.83 |
| 288.35 | 1.02 | 1.02 |
| 316.41 | 1.80 | 1.80 |
| 316.41 | 1.80 | 1.80 |
| 330.43 | 2.05 | 2.05 |
| 356.47 | 2.58 | 2.58 |
| 384.52 | 3.36 | 3.36 |
| 510.66 | 3.19 | 3.19 |
| 539.70 | 3.36 | 3.36 |
| 525.68 | 2.84 | 2.84 |
| 525.68 | 2.93 | 2.93 |