Assay Report Card

Basic Information

ID: ALA3591263

Type: Binding

Description: Irreversible inhibition of ERK1/2 in human Calu6 cells assessed as decrease in p90RSK phosphorylation at Thr359/Ser363 at 500 nM measured for up to 48 hrs after drug wash-out by immunoblot analysis

Organism: Homo sapiens

Cell type: Calu-6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
374.832.982.98