Basic Information
ID: ALA3591264
Type: Binding
Description: Inhibition of ERK1/2 in human A375 cells harboring B-RAF V600E mutant assessed as maximal decrease in p90RSK phosphorylation at Thr359/Ser363 measured between 20 and 30 hrs after drug treatment by immunoblot analysis
Organism: Homo sapiens
Cell type: A-375
Activity Charts
Bioactivity
Activity Types for Assay ALA3591264
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.83 | 2.98 | 2.98 |