Basic Information
ID: ALA3591344
Type: Binding
Description: Antagonist activity against mouse CCR2B expressed in human U2OS cells co-expressing beta-arrestin assessed as inhibition of mouse CCL2-induced beta-arrestin recruitment pre-incubated for 10 mins before mouse CCL2 stimulation for 90 mins by luminescence based assay
Organism: Mus musculus
Cell type: U2OS
Activity Charts
Bioactivity
Activity Types for Assay ALA3591344
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 531.14 | 6.78 | 6.78 |
| 514.51 | 5.68 | 5.68 |
| 528.54 | 6.07 | 6.07 |
| 544.54 | 5.69 | 5.69 |
| 464.50 | 4.80 | 4.80 |
| 478.53 | 5.19 | 5.19 |
| 494.53 | 4.81 | 4.81 |
| 608.60 | 7.22 | 7.22 |
| 622.62 | 7.61 | 7.61 |
| 638.62 | 7.23 | 7.23 |
| 558.59 | 6.34 | 6.34 |
| 572.62 | 6.73 | 6.73 |
| 588.62 | 6.35 | 6.35 |
| 574.59 | 6.04 | 6.04 |
| 554.57 | 6.32 | 6.32 |