Basic Information
ID: ALA3591483
Type: Binding
Description: Inhibition of N-terminal GST tagged full-length human PRMT8 expressed in Escherichia coli (BL21(DE3) pre-incubated for 30 mins before addition of a [3H]SAM and peptide mix
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3591483
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 288.40 | 2.25 | 2.25 |
| 302.42 | 2.52 | 2.52 |
| 286.42 | 2.67 | 2.67 |
| 322.41 | 3.26 | 3.26 |
| 322.84 | 2.91 | 2.91 |
| 336.87 | 3.17 | 3.17 |
| 350.89 | 3.18 | 3.18 |
| 332.45 | 1.88 | 1.88 |
| 346.48 | 2.12 | 2.12 |
| 390.84 | 3.93 | 3.93 |
| 432.49 | 4.37 | 4.37 |
| 438.54 | 5.10 | 5.10 |
| 428.50 | 3.53 | 3.53 |
| 442.60 | 3.47 | 3.47 |
| 373.50 | 1.57 | 1.57 |
| 432.57 | 2.36 | 2.36 |
| 407.52 | 3.22 | 3.22 |
| 407.52 | 3.22 | 3.22 |
| 248.31 | 1.61 | 1.61 |
| 288.40 | 2.13 | 2.13 |
| 393.49 | 2.88 | 2.88 |