Basic Information
ID: ALA3592371
Type: Binding
Description: Inhibition of Staphylococcus aureus DNA topoisomerase 4 assessed as residual enzyme activity at 100 uM using relaxed pNO1 plasmid and biotinylated oligonucelotide incubated for 30 mins by fluorescence based DNA relaxation assay
Format: BAO_0000223
Organism: Staphylococcus aureus
Target: Topoisomerase IV(ALA3038508)
Document: ALA3588817
Inhibition of Staphylococcus aureus DNA topoisomerase 4 assessed as residual enzyme activity at 100 uM using relaxed pNO1 plasmid and biotinylated oligonucelotide incubated for 30 mins by fluorescence based DNA relaxation assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3592371
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.40 | 2.49 | 2.49 |
| 420.13 | 2.87 | 2.87 |
| 426.50 | 2.80 | 2.80 |
| 384.42 | 1.93 | 1.93 |
| 398.44 | 2.32 | 2.32 |
| 412.47 | 2.71 | 2.71 |
| 331.23 | 2.65 | 2.65 |
| 431.30 | 2.57 | 2.57 |
| 445.33 | 2.96 | 2.96 |
| 417.27 | 2.48 | 2.48 |
| 431.30 | 2.87 | 2.87 |
| 326.19 | 1.98 | 1.98 |
| 336.19 | 1.44 | 1.44 |
| 415.09 | 2.20 | 2.20 |
| 307.36 | 1.83 | 1.83 |
| 515.16 | 2.12 | 2.12 |
| 420.13 | 2.87 | 2.87 |
| 520.20 | 2.79 | 2.79 |
| 534.23 | 3.18 | 3.18 |
| 520.20 | 2.79 | 2.79 |
| 441.31 | 2.02 | 2.02 |
| 506.18 | 2.70 | 2.70 |
| 427.28 | 1.93 | 1.93 |
| 462.17 | 3.24 | 3.24 |
| 505.19 | 2.10 | 2.10 |
| 412.47 | 2.41 | 2.41 |