Basic Information
ID: ALA3593137
Type: Binding
Description: Inhibition of ERK1/2 in human A375 cells harboring B-RAF V600E mutant assessed as decrease in phospho-RSK level after 2 hrs by Cellomics ArrayScanTM VTI imaging analysis
Organism: Homo sapiens
Cell type: A-375
Activity Charts
Bioactivity
Activity Types for Assay ALA3593137
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.34 | 4.67 | 4.67 |
| 587.69 | 3.69 | 3.69 |
| 362.38 | 1.60 | 1.60 |
| 324.41 | 0.90 | 0.90 |
| 300.34 | 2.51 | 2.51 |
| 304.38 | 1.61 | 1.61 |
| 326.42 | 0.78 | 0.78 |
| 302.36 | 2.39 | 2.39 |
| 422.39 | 4.13 | 4.13 |
| 360.85 | 3.43 | 3.43 |
| 412.39 | 3.93 | 3.93 |
| 372.86 | 4.19 | 4.19 |
| 373.84 | 3.59 | 3.59 |
| 375.86 | 3.81 | 3.81 |
| 374.83 | 2.98 | 2.98 |
| 407.40 | 3.95 | 3.95 |
| 353.43 | 3.24 | 3.24 |
| 369.82 | 3.48 | 3.48 |
| 414.94 | 4.28 | 4.28 |
| 349.40 | 3.13 | 3.13 |