Basic Information
ID: ALA3594913
Type: Binding
Description: Inhibition of HDAC1/2 in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 30 mins before substrate addition measured after 20 mins by UV-vis spectrophotometer analysis
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA3594913
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 400.19 | -0.38 | -0.38 |
| 428.24 | 0.40 | 0.40 |
| 456.29 | 1.18 | 1.18 |
| 488.29 | 2.15 | 2.15 |
| 401.35 | 1.13 | 1.13 |
| 417.81 | 1.64 | 1.64 |
| 462.26 | 1.75 | 1.75 |
| 383.36 | 0.99 | 0.99 |
| 397.39 | 1.30 | 1.30 |
| 428.36 | 0.90 | 0.90 |
| 431.83 | 2.03 | 2.03 |
| 445.86 | 2.42 | 2.42 |
| 476.28 | 2.14 | 2.14 |
| 490.31 | 2.53 | 2.53 |
| 490.31 | 2.53 | 2.53 |
| 504.34 | 2.92 | 2.92 |
| 475.30 | 2.81 | 2.81 |
| 461.27 | 2.72 | 2.72 |
| 551.40 | 3.86 | 3.86 |