Basic Information
ID: ALA3595291
Type: Binding
Description: Inhibition of human DNA topoisomerase IIalpha using plasmid pNO1 as a substrate after 30 mins
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA3593218
Inhibition of human DNA topoisomerase IIalpha using plasmid pNO1 as a substrate after 30 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3595291
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.49 | 3.76 | 3.76 |
| 371.49 | 3.76 | 3.76 |
| 371.49 | 3.76 | 3.76 |
| 359.45 | 3.89 | 3.89 |
| 359.45 | 3.89 | 3.89 |
| 386.46 | 3.66 | 3.66 |
| 386.46 | 3.66 | 3.66 |
| 386.46 | 3.66 | 3.66 |
| 375.91 | 4.40 | 4.40 |
| 375.91 | 4.40 | 4.40 |
| 375.91 | 4.40 | 4.40 |
| 366.47 | 3.62 | 3.62 |
| 366.47 | 3.62 | 3.62 |
| 366.47 | 3.62 | 3.62 |
| 384.46 | 3.76 | 3.76 |
| 293.42 | 2.96 | 2.96 |
| 307.44 | 3.35 | 3.35 |
| 305.43 | 2.96 | 2.96 |
| 319.46 | 3.35 | 3.35 |
| 347.51 | 4.13 | 4.13 |
| 293.30 | 1.74 | 1.74 |
| 276.25 | 1.33 | 1.33 |
| 286.24 | -0.38 | -0.38 |
| 291.26 | 1.47 | 1.47 |
| 302.14 | 3.03 | 3.03 |
| 299.12 | 2.71 | 2.71 |
| 329.19 | 2.85 | 2.85 |
| 297.19 | 4.22 | 4.22 |
| 269.14 | 3.48 | 3.48 |
| 285.13 | 2.46 | 2.46 |
| 319.98 | 3.68 | 3.68 |
| 285.13 | 2.80 | 2.80 |
| 323.78 | 1.23 | 1.23 |
| 323.78 | 1.57 | 1.57 |
| 205.24 | 1.12 | 1.12 |
| 250.24 | 1.03 | 1.03 |
| 219.27 | 1.43 | 1.43 |
| 251.34 | 1.75 | 1.75 |
| 398.25 | 2.99 | 2.99 |
| 466.49 | 2.94 | 2.94 |
| 602.67 | 4.41 | 4.41 |
| 584.63 | 4.03 | 4.03 |
| 329.45 | 3.66 | 3.66 |
| 311.39 | 1.69 | 1.69 |
| 355.83 | 3.42 | 3.42 |
| 385.86 | 3.42 | 3.42 |
| 220.26 | 1.08 | 1.08 |