Basic Information
ID: ALA3595792
Type: Binding
Description: Inhibition of human RAGE-amyloid beta-42 interaction at 4 uM preincubated for 30 mins measured after 1 hr by FRET assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3595792
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 585.75 | 7.95 | 7.95 |
| 585.75 | 7.95 | 7.95 |
| 485.63 | 6.39 | 6.39 |
| 485.63 | 6.39 | 6.39 |
| 434.51 | 6.54 | 6.54 |
| 446.52 | 6.68 | 6.68 |
| 448.49 | 5.53 | 5.53 |
| 547.63 | 6.75 | 6.75 |
| 484.52 | 7.42 | 7.42 |
| 496.53 | 7.56 | 7.56 |
| 498.50 | 6.41 | 6.41 |
| 597.63 | 7.63 | 7.63 |
| 484.52 | 7.42 | 7.42 |
| 496.53 | 7.56 | 7.56 |
| 498.50 | 6.41 | 6.41 |
| 597.63 | 7.63 | 7.63 |
| 521.01 | 7.72 | 7.72 |
| 420.90 | 6.07 | 6.07 |
| 434.92 | 6.41 | 6.41 |
| 448.95 | 6.80 | 6.80 |
| 462.98 | 7.19 | 7.19 |
| 462.93 | 6.33 | 6.33 |
| 535.04 | 7.97 | 7.97 |
| 434.92 | 6.32 | 6.32 |
| 462.98 | 7.05 | 7.05 |
| 477.00 | 7.44 | 7.44 |
| 525.05 | 8.23 | 8.23 |
| 476.96 | 6.58 | 6.58 |
| 436.94 | 6.66 | 6.66 |
| 448.95 | 6.81 | 6.81 |
| 450.92 | 5.65 | 5.65 |
| 550.06 | 6.87 | 6.87 |
| 422.91 | 6.27 | 6.27 |
| 448.95 | 6.81 | 6.81 |
| 564.08 | 7.31 | 7.31 |
| 564.08 | 7.31 | 7.31 |
| 463.97 | 5.74 | 5.74 |
| 463.97 | 5.74 | 5.74 |
| 462.98 | 7.20 | 7.20 |
| 519.09 | 8.47 | 8.47 |
| 539.08 | 8.59 | 8.59 |
| 464.95 | 6.04 | 6.04 |
| 463.97 | 5.61 | 5.61 |
| 477.99 | 5.96 | 5.96 |
| 508.02 | 5.32 | 5.32 |
| 522.00 | 6.09 | 6.09 |
| 536.03 | 6.48 | 6.48 |
| 564.08 | 7.12 | 7.12 |
| 550.06 | 6.87 | 6.87 |
| 564.08 | 7.26 | 7.26 |
| 540.06 | 7.53 | 7.53 |
| 542.04 | 6.32 | 6.32 |
| 472.63 | 7.70 | 7.70 |
| 484.64 | 7.84 | 7.84 |
| 486.61 | 6.69 | 6.69 |
| 470.61 | 7.45 | 7.45 |