Basic Information
ID: ALA3595952
Type: Binding
Description: Ratio of IC50 for displacement of [3H]-MK-801 from rat cortical membranes NMDA receptor in presence of 30 uM spermine to IC50 for displacement of [3H]-MK-801 from rat cortical membranes NMDA receptor in absence of 30 spermine
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA3595952
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.57 | 3.56 | 3.56 |
| 448.66 | 4.83 | 4.83 |
| 424.55 | 1.01 | 1.01 |
| 448.66 | 4.41 | 4.41 |
| 400.44 | 2.76 | 2.76 |
| 336.44 | 1.97 | 1.97 |
| 420.61 | 3.63 | 3.63 |
| 401.43 | 2.15 | 2.15 |
| 374.49 | 1.71 | 1.71 |
| 388.52 | 2.10 | 2.10 |
| 322.42 | 1.58 | 1.58 |
| 324.43 | 2.56 | 2.56 |
| 310.41 | 2.17 | 2.17 |
| 332.41 | 3.28 | 3.28 |
| 360.46 | 4.06 | 4.06 |
| 304.35 | 3.18 | 3.18 |
| 200.37 | 2.80 | 2.80 |
| 472.68 | 5.12 | 5.12 |
| 416.57 | 2.88 | 2.88 |
| 452.60 | 1.79 | 1.79 |
| 172.24 | -1.27 | -1.27 |
| 352.49 | 3.34 | 3.34 |
| 400.44 | 2.76 | 2.76 |
| 320.42 | 3.65 | 3.65 |
| 374.44 | 3.41 | 3.41 |
| 374.44 | 3.41 | 3.41 |
| 402.41 | 2.69 | 2.69 |
| 374.44 | 3.41 | 3.41 |
| 366.43 | 2.00 | 2.00 |
| 380.45 | 2.39 | 2.39 |
| 332.38 | 3.73 | 3.73 |
| 282.50 | 3.87 | 3.87 |
| 374.44 | 3.41 | 3.41 |
| 434.63 | 4.02 | 4.02 |
| 406.58 | 3.24 | 3.24 |
| 458.65 | 4.73 | 4.73 |
| 402.55 | 3.17 | 3.17 |
| 402.55 | 2.49 | 2.49 |
| 406.58 | 3.66 | 3.66 |
| 394.48 | 2.78 | 2.78 |
| 408.51 | 3.17 | 3.17 |
| 422.53 | 3.56 | 3.56 |
| 436.56 | 3.95 | 3.95 |
| 464.61 | 4.73 | 4.73 |
| 398.51 | 1.54 | 1.54 |
| 296.38 | 1.78 | 1.78 |
| 324.43 | 1.83 | 1.83 |
| 310.41 | 1.80 | 1.80 |
| 324.43 | 2.19 | 2.19 |
| 360.45 | 3.53 | 3.53 |
| 474.57 | 4.43 | 4.43 |
| 390.40 | 2.35 | 2.35 |
| 401.43 | 2.15 | 2.15 |
| 485.59 | 4.23 | 4.23 |
| 408.51 | 1.97 | 1.97 |
| 366.43 | 0.80 | 0.80 |
| 380.45 | 1.19 | 1.19 |
| 394.48 | 1.58 | 1.58 |
| 344.46 | 2.15 | 2.15 |
| 346.43 | 0.99 | 0.99 |
| 406.48 | 1.01 | 1.01 |
| 362.50 | 1.71 | 1.71 |
| 378.57 | 2.42 | 2.42 |
| 342.49 | 2.21 | 2.21 |
| 370.55 | 2.26 | 2.26 |
| 402.54 | 2.23 | 2.23 |
| 344.46 | 1.06 | 1.06 |
| 372.52 | 1.11 | 1.11 |
| 359.47 | 0.91 | 0.91 |
| 485.61 | 1.67 | 1.67 |
| 499.64 | 1.98 | 1.98 |
| 559.69 | 1.99 | 1.99 |
| 352.49 | 2.61 | 2.61 |
| 338.46 | 2.22 | 2.22 |
| 366.51 | 3.73 | 3.73 |
| 380.54 | 4.12 | 4.12 |
| 332.48 | 3.77 | 3.77 |
| 382.47 | 4.56 | 4.56 |
| 392.47 | 4.05 | 4.05 |