Basic Information
ID: ALA3599135
Type: Binding
Description: Inverse agonist activity at RORgamma in C57BL/6 mouse splenocytes assessed as reduction of IL-17 production after 2 days by ELISA
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA3599135
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 518.31 | 6.12 | 6.12 |
| 515.91 | 5.24 | 5.24 |
| 486.91 | 6.22 | 6.22 |
| 516.03 | 6.34 | 6.34 |
| 513.03 | 5.61 | 5.61 |
| 501.02 | 5.76 | 5.76 |
| 515.05 | 6.15 | 6.15 |
| 510.01 | 5.61 | 5.61 |
| 529.49 | 6.13 | 6.13 |
| 492.61 | 5.27 | 5.27 |
| 527.06 | 6.00 | 6.00 |
| 539.07 | 6.00 | 6.00 |
| 541.09 | 6.25 | 6.25 |
| 569.10 | 5.37 | 5.37 |
| 569.10 | 5.37 | 5.37 |
| 529.03 | 4.59 | 4.59 |
| 528.05 | 5.41 | 5.41 |
| 596.12 | 5.52 | 5.52 |
| 539.07 | 6.15 | 6.15 |
| 525.04 | 5.76 | 5.76 |
| 525.04 | 5.44 | 5.44 |
| 513.02 | 5.54 | 5.54 |