Basic Information
ID: ALA3599261
Type: Functional
Description: Antagonist activity at human CysLT2 expressed in HEK293 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins prior to LTD4 addition measured after 1 hr by Fura 2-AM dye-based fluorescence assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3599261
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 595.73 | 6.28 | 6.28 |
| 532.59 | 4.86 | 4.86 |
| 527.62 | 6.54 | 6.54 |
| 527.62 | 6.54 | 6.54 |
| 511.62 | 6.71 | 6.71 |
| 546.06 | 7.36 | 7.36 |
| 565.59 | 7.12 | 7.12 |
| 543.64 | 7.15 | 7.15 |
| 560.09 | 7.67 | 7.67 |
| 525.65 | 7.01 | 7.01 |
| 555.67 | 7.02 | 7.02 |
| 579.62 | 7.43 | 7.43 |
| 597.61 | 7.57 | 7.57 |
| 597.61 | 7.57 | 7.57 |
| 597.61 | 7.57 | 7.57 |
| 557.66 | 7.46 | 7.46 |
| 574.12 | 7.98 | 7.98 |
| 544.05 | 6.42 | 6.42 |
| 558.07 | 6.81 | 6.81 |
| 572.10 | 7.20 | 7.20 |
| 558.07 | 6.81 | 6.81 |
| 572.10 | 7.20 | 7.20 |
| 586.13 | 7.60 | 7.60 |
| 572.10 | 7.20 | 7.20 |
| 586.13 | 7.60 | 7.60 |
| 600.16 | 7.99 | 7.99 |
| 586.13 | 7.60 | 7.60 |
| 600.16 | 7.99 | 7.99 |
| 614.18 | 8.38 | 8.38 |
| 618.15 | 8.12 | 8.12 |
| 618.15 | 8.12 | 8.12 |
| 618.15 | 8.12 | 8.12 |
| 623.64 | 7.58 | 7.58 |
| 641.63 | 7.72 | 7.72 |
| 583.70 | 7.47 | 7.47 |
| 601.69 | 7.61 | 7.61 |