Basic Information
ID: ALA3599287
Type: Functional
Description: Antagonist activity at guinea pig CysLT1 expressed in CHOK1 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins prior to LTD4 addition measured after 1 hr by Fura 2-AM dye-based fluorescence assay
Organism: Cavia porcellus
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA3599287
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 600.16 | 7.99 | 7.99 |
| 618.15 | 8.12 | 8.12 |
| 623.64 | 7.58 | 7.58 |
| 641.63 | 7.72 | 7.72 |
| 583.70 | 7.47 | 7.47 |
| 601.69 | 7.61 | 7.61 |