Basic Information
ID: ALA3599915
Type: Functional
Description: Negative allosteric modulatory activity at human cloned mGluR5 receptor expressed in CHO-T-Rex cells assessed as inhibiton of quisqualate-induced calcium mobilization treated 10 mins prior to agonist application by fluorescence analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3599915
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 200.27 | 2.25 | 2.25 |
| 193.25 | 2.79 | 2.79 |
| 277.35 | 3.31 | 3.31 |
| 266.69 | 1.29 | 1.29 |
| 336.35 | 1.69 | 1.69 |
| 362.39 | 2.33 | 2.33 |
| 319.36 | 3.57 | 3.57 |
| 320.35 | 2.96 | 2.96 |
| 334.38 | 3.27 | 3.27 |
| 288.39 | 3.97 | 3.97 |
| 333.39 | 3.88 | 3.88 |
| 333.39 | 3.88 | 3.88 |
| 353.81 | 4.22 | 4.22 |
| 359.39 | 3.14 | 3.14 |
| 390.49 | 4.90 | 4.90 |
| 348.41 | 3.58 | 3.58 |