Assay Report Card

Basic Information

ID: ALA3600000

Type: Binding

Description: Inhibition of recombinant mouse RANKL-induced osteoclastogenesis of mouse RAW264.7 cells assessed as suppression of NFATc1 mRNA expression at 2.5 to 5 uM preincubated for 1 hr followed by RANKL addition measured after 24 hrs by RT-PCR analysis

Organism: Mus musculus

Cell type: RAW264.7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
387.294.174.17
375.333.873.87