Basic Information
ID: ALA3600002
Type: Binding
Description: Inhibition of recombinant mouse RANKL-induced osteoclastogenesis of mouse RAW264.7 cells assessed as suppression of TRAP mRNA expression at 2.5 to 5 uM preincubated for 1 hr followed by RANKL addition measured after 24 hrs by RT-PCR analysis
Format: BAO_0000219
Organism: Mus musculus
Cell type: RAW264.7
Target: Tumor necrosis factor ligand superfamily member 11(ALA3596084)
Document: ALA3596168
Inhibition of recombinant mouse RANKL-induced osteoclastogenesis of mouse RAW264.7 cells assessed as suppression of TRAP mRNA expression at 2.5 to 5 uM preincubated for 1 hr followed by RANKL addition measured after 24 hrs by RT-PCR analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3600002
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 387.29 | 4.17 | 4.17 |
| 375.33 | 3.87 | 3.87 |