Basic Information
ID: ALA3600045
Type: Functional
Description: Negative allosteric modulatory activity at rat cloned mGluR1 receptor expressed in CHO-T-Rex cells assessed as inhibiton of quisqualate-induced calcium mobilization treated 10 mins prior to agonist application by fluorescence analysis
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA3600045
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 336.35 | 1.69 | 1.69 |
| 319.36 | 3.57 | 3.57 |
| 320.35 | 2.96 | 2.96 |
| 334.38 | 3.27 | 3.27 |
| 333.39 | 3.88 | 3.88 |
| 333.39 | 3.88 | 3.88 |
| 353.81 | 4.22 | 4.22 |