Basic Information
ID: ALA3600166
Type: Functional
Description: Negative allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as effect on quisqualate-induced inositol phosphate accumulation incubated for 30 mins by florescence assay
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: HEK293
Target: Metabotropic glutamate receptor 5(ALA2564)
Document: ALA3596138
Negative allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as effect on quisqualate-induced inositol phosphate accumulation incubated for 30 mins by florescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3600166
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 193.25 | 2.79 | 2.79 |
| 381.82 | 4.25 | 4.25 |
| 362.82 | 4.40 | 4.40 |
| 362.82 | 4.40 | 4.40 |