Basic Information
ID: ALA3600176
Type: Binding
Description: Inverse agonist activity at GAL4-fused human RORa expressed in HEK293T cells assessed as suppression of basal transcriptional activity after 20 hrs by dual-glo luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-293T
Target: Nuclear receptor ROR-alpha(ALA5868)
Document: ALA3596163
Inverse agonist activity at GAL4-fused human RORa expressed in HEK293T cells assessed as suppression of basal transcriptional activity after 20 hrs by dual-glo luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3600176
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.82 | 5.63 | 5.63 |
| 438.89 | 5.49 | 5.49 |
| 433.85 | 4.56 | 4.56 |
| 444.80 | 5.60 | 5.60 |
| 460.80 | 5.31 | 5.31 |
| 462.79 | 5.74 | 5.74 |