Basic Information
ID: ALA3602073
Type: Binding
Description: Inhibition of JAK3 (unknown origin) expressed in mouse BA/F3 cells assessed as reduction of STAT5 phosphorylation at 300 nM incubated for 3 hrs followed by washout measured after 4 hrs by immunoblotting analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: BaF3
Target: Tyrosine-protein kinase JAK3(ALA2148)
Document: ALA3600288
Inhibition of JAK3 (unknown origin) expressed in mouse BA/F3 cells assessed as reduction of STAT5 phosphorylation at 300 nM incubated for 3 hrs followed by washout measured after 4 hrs by immunoblotting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3602073
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 427.90 | 3.45 | 3.45 |
| 413.87 | 2.80 | 2.80 |
| 508.03 | 4.37 | 4.37 |