Basic Information
ID: ALA3602079
Type: Binding
Description: Inhibition of JAK1 in mouse BMDM assessed as inhibition of IFNbeta-induced STAT1 phosphorylation at 5 uM preincubated for 3 hrs followed by IFNbeta induction measured after 30 mins by immunoblotting
Format: BAO_0000357
Organism: Mus musculus
Target: Tyrosine-protein kinase JAK1(ALA2968)
Document: ALA3600288
Inhibition of JAK1 in mouse BMDM assessed as inhibition of IFNbeta-induced STAT1 phosphorylation at 5 uM preincubated for 3 hrs followed by IFNbeta induction measured after 30 mins by immunoblotting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3602079
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.90 | 3.45 | 3.45 |
| 413.87 | 2.80 | 2.80 |
| 508.03 | 4.37 | 4.37 |