Inhibition of JAK2 in mouse BMDM assessed as inhibition of GM-CSF-induced STAT5 phosphorylation at 5 uM preincubated for 3 hrs followed by GM-CSF indu...

Basic Information

ID: ALA3602080

Type: Binding

Description: Inhibition of JAK2 in mouse BMDM assessed as inhibition of GM-CSF-induced STAT5 phosphorylation at 5 uM preincubated for 3 hrs followed by GM-CSF induction measured after 30 mins by immunoblotting

Format: BAO_0000357

Organism: Mus musculus

Target: Tyrosine-protein kinase JAK2(ALA1649049)

Document: ALA3600288

Inhibition of JAK2 in mouse BMDM assessed as inhibition of GM-CSF-induced STAT5 phosphorylation at 5 uM preincubated for 3 hrs followed by GM-CSF induction measured after 30 mins by immunoblotting: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3602080

Inhibition

Total(3)

Parent Molecular Weight	ALogP	Polar Surface Area
427.90	3.45	3.45
413.87	2.80	2.80
508.03	4.37	4.37

Parent Molecular Weight

ALogP

Polar Surface Area

427.90

3.45

413.87

2.80

508.03

4.37

Inhibition of JAK2 in mouse BMDM assessed as inhibition of GM-CSF-induced STAT5 phosphorylation at 5 uM preincubated for 3 hrs followed by GM-CSF indu...

Basic Information

Activity Charts

Compound Summary