Basic Information
ID: ALA3602082
Type: Binding
Description: Inhibition of JAK3 in mouse BMDM assessed as inhibition of IL-4 induced STAT6 phosphorylation at 10 uM incubated for 3 hrs prior to compound washout for 8 to 24 hrs and followed by IL-4 induction measured after 30 mins by immunoblotting
Format: BAO_0000357
Organism: Mus musculus
Target: Tyrosine-protein kinase JAK3(ALA5250)
Document: ALA3600288
Inhibition of JAK3 in mouse BMDM assessed as inhibition of IL-4 induced STAT6 phosphorylation at 10 uM incubated for 3 hrs prior to compound washout for 8 to 24 hrs and followed by IL-4 induction measured after 30 mins by immunoblotting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3602082
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.90 | 3.45 | 3.45 |
| 413.87 | 2.80 | 2.80 |