Basic Information
ID: ALA3602084
Type: Binding
Description: Inhibition of JAK3 in human TALL-1 cells assessed as inhibition of IL-2 induced STAT5 phosphorylation at 100 nM preincubated for 3 hrs followed by IL-2 induction measured after 30 mins by immunoblotting
Format: BAO_0000219
Organism: Homo sapiens
Cell type: TALL-1
Target: Tyrosine-protein kinase JAK3(ALA2148)
Document: ALA3600288
Inhibition of JAK3 in human TALL-1 cells assessed as inhibition of IL-2 induced STAT5 phosphorylation at 100 nM preincubated for 3 hrs followed by IL-2 induction measured after 30 mins by immunoblotting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3602084
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.90 | 3.45 | 3.45 |
| 413.87 | 2.80 | 2.80 |