Basic Information
ID: ALA3602085
Type: Binding
Description: Inhibition of JAK2 in human OCL-AML5 cells assessed as inhibition of GM-CSF induced STAT5 phosphorylation up to 10 uM preincubated for 3 hrs followed by GM-CSF induction measured after 30 mins by immunoblotting
Format: BAO_0000219
Organism: Homo sapiens
Cell type: OCL-AML5
Target: Tyrosine-protein kinase JAK2(ALA2971)
Document: ALA3600288
Inhibition of JAK2 in human OCL-AML5 cells assessed as inhibition of GM-CSF induced STAT5 phosphorylation up to 10 uM preincubated for 3 hrs followed by GM-CSF induction measured after 30 mins by immunoblotting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3602085
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.90 | 3.45 | 3.45 |
| 413.87 | 2.80 | 2.80 |
| 508.03 | 4.37 | 4.37 |