Basic Information
ID: ALA3602131
Type: Binding
Description: Inhibition of WNV NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate preincubated for 15 mins followed by substrate addition measured for 15 mins by FRET assay
Organism: West Nile virus
Activity Charts
Bioactivity
Activity Types for Assay ALA3602131
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 707.86 | 1.45 | 1.45 |
| 721.89 | 1.70 | 1.70 |
| 735.91 | 2.09 | 2.09 |
| 735.91 | 2.09 | 2.09 |
| 749.94 | 2.48 | 2.48 |
| 721.89 | 1.84 | 1.84 |
| 735.91 | 2.23 | 2.23 |
| 749.94 | 2.48 | 2.48 |
| 719.87 | 1.59 | 1.59 |
| 733.90 | 1.84 | 1.84 |
| 747.92 | 2.23 | 2.23 |
| 747.92 | 2.37 | 2.37 |
| 761.95 | 2.62 | 2.62 |
| 775.98 | 3.01 | 3.01 |
| 761.95 | 2.76 | 2.76 |
| 814.03 | 3.26 | 3.26 |
| 703.83 | 0.67 | 0.67 |
| 717.85 | 1.06 | 1.06 |
| 731.88 | 1.45 | 1.45 |