Basic Information
ID: ALA3602926
Type: Binding
Description: Inhibition of Keap1-Nrf2 protein-protein interaction in human HepG2-ARE-C8 cells assessed as induction of Nrf2 activation at 0.1 uM incubated for 12 hrs by ARE-luciferase reporter gene assay relative to untreated control
Organism: Homo sapiens
Cell type: HepG2-ARE-C8
Activity Charts
Bioactivity
Activity Types for Assay ALA3602926
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 614.65 | 3.42 | 3.42 |
| 582.66 | 4.02 | 4.02 |
| 590.58 | 3.68 | 3.68 |
| 623.49 | 4.71 | 4.71 |
| 712.39 | 4.92 | 4.92 |
| 668.71 | 3.32 | 3.32 |
| 666.82 | 5.99 | 5.99 |
| 638.76 | 5.25 | 5.25 |
| 554.60 | 3.40 | 3.40 |
| 722.59 | 5.20 | 5.20 |
| 654.72 | 5.71 | 5.71 |
| 690.60 | 5.44 | 5.44 |
| 614.65 | 3.42 | 3.42 |
| 604.62 | 3.14 | 3.14 |
| 666.82 | 6.08 | 6.08 |