Basic Information
ID: ALA3606528
Type: Binding
Description: Inhibition of mPGES-1 in IL-1beta-stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 formation incubated for 15 mins using PGH2 substrate by RP-HPLC method
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA3606528
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 309.34 | 3.99 | 3.99 |
| 472.09 | 8.01 | 8.01 |
| 402.44 | 3.64 | 3.64 |
| 329.33 | 4.36 | 4.36 |
| 397.33 | 5.38 | 5.38 |
| 359.36 | 4.37 | 4.37 |
| 363.78 | 5.02 | 5.02 |
| 439.90 | 5.46 | 5.46 |
| 379.84 | 5.45 | 5.45 |
| 424.29 | 5.56 | 5.56 |
| 375.42 | 4.80 | 4.80 |
| 365.82 | 5.52 | 5.52 |
| 430.81 | 6.73 | 6.73 |
| 518.59 | 6.91 | 6.91 |
| 502.62 | 7.02 | 7.02 |
| 469.97 | 6.97 | 6.97 |
| 324.18 | 4.38 | 4.38 |
| 351.61 | 5.30 | 5.30 |
| 353.58 | 4.96 | 4.96 |
| 408.26 | 5.98 | 5.98 |
| 380.84 | 4.79 | 4.79 |
| 452.71 | 6.09 | 6.09 |
| 412.87 | 5.37 | 5.37 |
| 358.49 | 5.47 | 5.47 |
| 446.59 | 5.97 | 5.97 |
| 416.52 | 6.32 | 6.32 |
| 290.16 | 4.00 | 4.00 |
| 358.63 | 5.19 | 5.19 |
| 358.63 | 5.19 | 5.19 |
| 338.21 | 4.85 | 4.85 |
| 338.21 | 4.85 | 4.85 |
| 338.21 | 4.85 | 4.85 |
| 403.08 | 5.30 | 5.30 |
| 388.65 | 5.20 | 5.20 |
| 466.37 | 5.96 | 5.96 |
| 396.45 | 3.97 | 3.97 |
| 313.74 | 2.69 | 2.69 |
| 259.69 | 3.16 | 3.16 |
| 542.47 | 7.62 | 7.62 |
| 379.26 | 3.09 | 3.09 |
| 394.86 | 4.41 | 4.41 |
| 434.93 | 3.99 | 3.99 |
| 483.62 | 6.00 | 6.00 |
| 382.39 | 6.09 | 6.09 |
| 364.38 | 5.09 | 5.09 |
| 416.52 | 6.00 | 6.00 |