Basic Information
ID: ALA3606534
Type: Functional
Description: Antagonist activity at CCR5 (unknown origin) expressed in human MOLT4 cells assessed as inhibition of CCL5-induced calcium mobilization after 1 hr
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MOLT-4
Target: C-C chemokine receptor type 5(ALA274)
Document: ALA3603778
Antagonist activity at CCR5 (unknown origin) expressed in human MOLT4 cells assessed as inhibition of CCL5-induced calcium mobilization after 1 hr: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3606534
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 550.10 | 5.70 | 5.70 |
| 602.18 | 6.73 | 6.73 |
| 614.27 | 7.49 | 7.49 |
| 562.20 | 5.99 | 5.99 |
| 534.14 | 5.64 | 5.64 |
| 607.77 | 4.92 | 4.92 |
| 518.87 | 4.70 | 4.70 |
| 585.98 | 5.43 | 5.43 |
| 539.98 | 3.21 | 3.21 |
| 485.96 | 3.68 | 3.68 |
| 500.00 | 3.14 | 3.14 |
| 480.01 | 2.56 | 2.56 |
| 542.17 | 4.84 | 4.84 |
| 510.03 | 3.41 | 3.41 |
| 506.09 | 4.52 | 4.52 |
| 478.04 | 4.01 | 4.01 |
| 449.98 | 3.40 | 3.40 |