Basic Information
ID: ALA3606556
Type: Binding
Description: Antagonist activity at P2X7 receptor in human whole blood assessed as inhibition of BzATP-induced IL1beta release incubated 30 mins prior to BzATP-challenge measured after 1.5 hrs by ELISA method
Format: BAO_0000357
Organism: Homo sapiens
Tissue: Blood
Target: P2X purinoceptor 7(ALA4805)
Document: ALA3603800
Antagonist activity at P2X7 receptor in human whole blood assessed as inhibition of BzATP-induced IL1beta release incubated 30 mins prior to BzATP-challenge measured after 1.5 hrs by ELISA method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3606556
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.26 | 3.86 | 3.86 |
| 405.26 | 4.44 | 4.44 |
| 438.81 | 4.80 | 4.80 |
| 422.80 | 3.45 | 3.45 |
| 388.26 | 3.69 | 3.69 |
| 418.28 | 3.70 | 3.70 |
| 406.25 | 3.83 | 3.83 |