Basic Information
ID: ALA3607180
Type: Binding
Description: Antagonist activity against human S1P1 receptor expressed in human U2OS cells co-expressing GFP assessed as inhibition of S1P-induced receptor translocation
Organism: Homo sapiens
Cell type: U2OS
Activity Charts
Bioactivity
Activity Types for Assay ALA3607180
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 342.85 | 2.55 | 2.55 |
| 363.87 | 3.75 | 3.75 |
| 393.90 | 3.76 | 3.76 |
| 431.87 | 4.77 | 4.77 |
| 416.31 | 4.54 | 4.54 |
| 388.88 | 3.62 | 3.62 |
| 393.90 | 3.24 | 3.24 |
| 393.90 | 3.24 | 3.24 |
| 406.90 | 2.85 | 2.85 |
| 420.97 | 3.81 | 3.81 |
| 448.98 | 3.59 | 3.59 |
| 441.96 | 3.15 | 3.15 |
| 398.32 | 4.40 | 4.40 |
| 364.86 | 3.14 | 3.14 |
| 364.86 | 3.14 | 3.14 |
| 364.86 | 3.14 | 3.14 |
| 364.86 | 3.14 | 3.14 |
| 361.39 | 3.22 | 3.22 |
| 389.44 | 4.00 | 4.00 |
| 397.42 | 4.11 | 4.11 |
| 415.41 | 4.25 | 4.25 |
| 411.45 | 4.42 | 4.42 |
| 422.43 | 3.99 | 3.99 |
| 431.87 | 4.77 | 4.77 |
| 422.43 | 3.99 | 3.99 |
| 468.50 | 4.38 | 4.38 |
| 453.53 | 5.31 | 5.31 |
| 451.39 | 4.53 | 4.53 |
| 398.41 | 3.51 | 3.51 |
| 398.41 | 3.51 | 3.51 |
| 398.41 | 3.51 | 3.51 |
| 415.44 | 3.16 | 3.16 |
| 443.50 | 4.03 | 4.03 |
| 415.44 | 3.33 | 3.33 |
| 429.47 | 3.64 | 3.64 |
| 443.50 | 4.03 | 4.03 |
| 443.50 | 4.20 | 4.20 |
| 415.44 | 3.16 | 3.16 |
| 415.44 | 3.16 | 3.16 |
| 461.49 | 3.53 | 3.53 |
| 355.42 | 2.36 | 2.36 |
| 385.45 | 2.37 | 2.37 |
| 423.42 | 3.38 | 3.38 |
| 395.49 | 3.24 | 3.24 |
| 386.44 | 1.77 | 1.77 |
| 424.41 | 2.78 | 2.78 |
| 396.48 | 2.63 | 2.63 |