Basic Information
ID: ALA3607349
Type: Binding
Description: Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measured after 15 mins by immunocytochemical analysis
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA3607349
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 218.26 | 1.15 | 1.15 |
| 248.28 | 0.78 | 0.78 |
| 303.36 | 0.46 | 0.46 |
| 301.39 | 1.62 | 1.62 |
| 335.41 | 1.80 | 1.80 |
| 377.49 | 2.96 | 2.96 |
| 363.46 | 2.65 | 2.65 |
| 363.46 | 2.71 | 2.71 |
| 363.46 | 2.71 | 2.71 |
| 363.46 | 2.71 | 2.71 |
| 428.33 | 3.17 | 3.17 |
| 428.33 | 3.17 | 3.17 |
| 417.43 | 3.42 | 3.42 |
| 392.50 | 2.47 | 2.47 |
| 350.42 | 1.80 | 1.80 |
| 350.42 | 1.80 | 1.80 |
| 350.42 | 1.80 | 1.80 |
| 355.46 | 2.47 | 2.47 |
| 352.44 | 1.74 | 1.74 |
| 388.47 | 2.89 | 2.89 |
| 343.43 | 1.38 | 1.38 |
| 377.44 | 2.78 | 2.78 |
| 395.43 | 2.92 | 2.92 |
| 395.43 | 2.92 | 2.92 |
| 411.88 | 3.44 | 3.44 |
| 428.34 | 3.46 | 3.46 |