Assay Report Card

Basic Information

ID: ALA3607645

Type: Functional

Description: Antitumor activity activity against human NCI-H2228 cells xenografted in Balb/c mouse EML4-ALK NSCLC model assessed as reduction in tumor growth at 3 to 30 mg/kg, po qd for 2 weeks

Organism: Homo sapiens

Cell type: NCI-H2228

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
672.275.445.44