Basic Information
ID: ALA3607814
Type: Binding
Description: Potency index, ratio of IC50 for compound-1 to IC50 for test compound for binding affinity to human IgG1-fused human Siglec-7-FC (Gln19 to Gly357 residues) assessed as inhibition Siglec-7-Fc binding to to RBC pre-incubated for 10 mins before 20 mins incubation with RBCs by flow cytometry
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3607814
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 345.28 | -3.22 | -3.22 |
| 415.33 | -4.61 | -4.61 |
| 429.36 | -4.35 | -4.35 |
| 443.39 | -3.96 | -3.96 |
| 457.41 | -3.57 | -3.57 |
| 471.44 | -3.18 | -3.18 |
| 471.44 | -3.18 | -3.18 |
| 491.43 | -2.46 | -2.46 |
| 505.46 | -2.78 | -2.78 |
| 581.55 | -1.11 | -1.11 |