Basic Information
ID: ALA3609987
Type: Binding
Description: Inhibition of EGFR L858R/T790M double mutant in human H1975 cells assessed as inhibition of phosphorylation at Y1068 after 2 hrs by sandwich ELISA method
Organism: Homo sapiens
Cell type: H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA3609987
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.46 | 1.71 | 1.71 |
| 515.67 | 2.98 | 2.98 |
| 491.60 | 1.19 | 1.19 |
| 427.49 | 2.02 | 2.02 |
| 512.59 | 2.06 | 2.06 |
| 429.46 | 1.16 | 1.16 |