Inhibition of CCR5 assessed as reduction in fusion of effector cells expressing JRFL envelope (CCR5-tropic/CD4-dependent) with human HeLa-C14 target c...

Basic Information

ID: ALA3610409

Type: Binding

Description: Inhibition of CCR5 assessed as reduction in fusion of effector cells expressing JRFL envelope (CCR5-tropic/CD4-dependent) with human HeLa-C14 target cells expressing CD4, CCR5, and CXCR4) by luciferase readout

Format: BAO_0000219

Organism: Homo sapiens

Target:  C-C chemokine receptor type 5(ALA274)

Document:  ALA3608277

Inhibition of CCR5 assessed as reduction in fusion of effector cells expressing JRFL envelope (CCR5-tropic/CD4-dependent) with human HeLa-C14 target cells expressing CD4, CCR5, and CXCR4) by luciferase readout: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
332.453.783.78