Inhibition of CXCR4 assessed as reduction in fusion of human ACTOne-X4 cells as target cells expressing only CXCR4) with effector cells expressing HIV...

Basic Information

ID: ALA3610414

Type: Binding

Description: Inhibition of CXCR4 assessed as reduction in fusion of human ACTOne-X4 cells as target cells expressing only CXCR4) with effector cells expressing HIV-8x envelope (CD4-independent requiring only CXCR4 and not CD4)

Format: BAO_0000219

Organism: Homo sapiens

Cell type: ACTOne-X4

Target: C-X-C chemokine receptor type 4(ALA2107)

Document: ALA3608277

Inhibition of CXCR4 assessed as reduction in fusion of human ACTOne-X4 cells as target cells expressing only CXCR4) with effector cells expressing HIV-8x envelope (CD4-independent requiring only CXCR4 and not CD4): 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3610414

EC50

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
332.45	3.78	3.78

Parent Molecular Weight

ALogP

Polar Surface Area

332.45

3.78

Inhibition of CXCR4 assessed as reduction in fusion of human ACTOne-X4 cells as target cells expressing only CXCR4) with effector cells expressing HIV...

Basic Information

Activity Charts

Compound Summary