Inhibition of CXCR4 in human Jurkat cells assessed as reduction in HIV-Nef-M1-induced mitochondrial membrane depolarization at 0.01 to 100 uM by JC1 d...

Basic Information

ID: ALA3610417

Type: Binding

Description: Inhibition of CXCR4 in human Jurkat cells assessed as reduction in HIV-Nef-M1-induced mitochondrial membrane depolarization at 0.01 to 100 uM by JC1 dye based fluorescence depolarization assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: Jurkat

Target:  C-X-C chemokine receptor type 4(ALA2107)

Document:  ALA3608277

Inhibition of CXCR4 in human Jurkat cells assessed as reduction in HIV-Nef-M1-induced mitochondrial membrane depolarization at 0.01 to 100 uM by JC1 dye based fluorescence depolarization assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
502.800.420.42
267.24-0.20-0.20
513.685.955.95
332.453.783.78