Prodrug conversion in dog liver S9 fractions assessed as formation of 1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl)pyrimidin-5-yl]-7-[(2R)-tetra...

Basic Information

ID: ALA3610482

Type: ADME

Description: Prodrug conversion in dog liver S9 fractions assessed as formation of 1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl)pyrimidin-5-yl]-7-[(2R)-tetrahydrofuran-2-yl]-1H-benzimidazol-2-yl]urea by Michaelis-Menten plot analysis

Format: BAO_0000220

Organism: Canis lupus familiaris

Tissue: Liver

Subcellular Fraction: Liver S9 fraction

Target:  Liver(ALA613430)

Document:  ALA3608279

Prodrug conversion in dog liver S9 fractions assessed as formation of 1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl)pyrimidin-5-yl]-7-[(2R)-tetrahydrofuran-2-yl]-1H-benzimidazol-2-yl]urea by Michaelis-Menten plot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
508.453.503.50