ID: ALA3610482
Type: ADME
Description: Prodrug conversion in dog liver S9 fractions assessed as formation of 1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl)pyrimidin-5-yl]-7-[(2R)-tetrahydrofuran-2-yl]-1H-benzimidazol-2-yl]urea by Michaelis-Menten plot analysis
Format: BAO_0000220
Organism: Canis lupus familiaris
Tissue: Liver
Subcellular Fraction: Liver S9 fraction
Target: Liver(ALA613430)
Document: ALA3608279
Prodrug conversion in dog liver S9 fractions assessed as formation of 1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl)pyrimidin-5-yl]-7-[(2R)-tetrahydrofuran-2-yl]-1H-benzimidazol-2-yl]urea by Michaelis-Menten plot analysis: 1
Bioactivity
Activity Types for Assay ALA3610482
Km
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
508.45 | 3.50 | 3.50 |