Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced mean current response by m...

Basic Information

ID: ALA3610683

Type: Binding

Description: Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced mean current response by measuring remaining current at 100 uM by two-electrode voltage clamp electrophysiology assay relative to control

Format: BAO_0000219

Organism: Rattus norvegicus

Target: Neuronal acetylcholine receptor protein alpha-7 subunit(ALA4980)

Document: ALA3608275

Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced mean current response by measuring remaining current at 100 uM by two-electrode voltage clamp electrophysiology assay relative to control: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3610683

Inhibition

Total(13)

Parent Molecular Weight	ALogP	Polar Surface Area
162.24	1.85	1.85
269.32	2.89	2.89
208.69	2.34	2.34
211.27	1.80	1.80
251.33	2.75	2.75
269.32	2.89	2.89
285.78	3.40	3.40
266.35	2.33	2.33
281.36	2.76	2.76
251.33	2.75	2.75
285.78	3.40	3.40
266.35	2.33	2.33
281.36	2.76	2.76

Parent Molecular Weight

ALogP

Polar Surface Area

162.24

1.85

269.32

2.89

208.69

2.34

211.27

1.80

251.33

2.75

269.32

2.89

285.78

3.40

266.35

2.33

281.36

2.76