Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced mean current response...

Basic Information

ID: ALA3610961

Type: Binding

Description: Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced mean current response by two-electrode voltage clamp electrophysiology assay

Format: BAO_0000219

Organism: Rattus norvegicus

Target: Neuronal acetylcholine receptor; alpha3/beta4(ALA1907593)

Document: ALA3608275

Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced mean current response by two-electrode voltage clamp electrophysiology assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3610961

IC50

Total(8)

Parent Molecular Weight	ALogP	Polar Surface Area
269.32	2.89	2.89
251.33	2.75	2.75
269.32	2.89	2.89
285.78	3.40	3.40
281.36	2.76	2.76
251.33	2.75	2.75
285.78	3.40	3.40
281.36	2.76	2.76

Parent Molecular Weight

ALogP

Polar Surface Area

269.32

2.89

251.33

2.75

269.32

2.89

285.78

3.40

281.36

2.76