Basic Information
ID: ALA3611367
Type: Binding
Description: Inhibition of recombinant Cav1.2 channel (unknown origin) expressed in HEK293 cells assessed as effect on calcium flux incubated for 3 mins by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Voltage-gated L-type calcium channel alpha-1C subunit(ALA1940)
Document: ALA3608217
Inhibition of recombinant Cav1.2 channel (unknown origin) expressed in HEK293 cells assessed as effect on calcium flux incubated for 3 mins by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3611367
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 495.64 | 5.27 | 5.27 |
| 523.69 | 6.43 | 6.43 |
| 599.79 | 8.00 | 8.00 |
| 599.79 | 8.00 | 8.00 |
| 509.67 | 5.77 | 5.77 |
| 509.67 | 5.77 | 5.77 |
| 461.61 | 4.81 | 4.81 |
| 459.63 | 5.82 | 5.82 |
| 457.62 | 5.57 | 5.57 |
| 473.66 | 6.21 | 6.21 |
| 459.63 | 5.82 | 5.82 |
| 473.66 | 6.21 | 6.21 |
| 503.69 | 6.22 | 6.22 |
| 403.57 | 5.27 | 5.27 |
| 461.61 | 4.61 | 4.61 |
| 493.67 | 6.28 | 6.28 |
| 523.69 | 6.01 | 6.01 |
| 551.75 | 7.00 | 7.00 |
| 523.69 | 6.43 | 6.43 |