Inhibition of SHP2 in human NCI-H1975 cells assessed as reduction of EGF-induced ERK1/2 activation at 40 uM after 60 mins relative to control

Basic Information

ID: ALA3611708

Type: Binding

Description: Inhibition of SHP2 in human NCI-H1975 cells assessed as reduction of EGF-induced ERK1/2 activation at 40 uM after 60 mins relative to control

Format: BAO_0000219

Organism: Homo sapiens

Cell type: NCI-H1975

Target: Protein-tyrosine phosphatase 2C(ALA3864)

Document: ALA3608232

Inhibition of SHP2 in human NCI-H1975 cells assessed as reduction of EGF-induced ERK1/2 activation at 40 uM after 60 mins relative to control: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3611708

Total(2)

Parent Molecular Weight	ALogP	Polar Surface Area
579.37	3.44	3.44
453.48	2.83	2.83

Parent Molecular Weight

ALogP

Polar Surface Area

579.37

3.44

453.48

2.83

Inhibition of SHP2 in human NCI-H1975 cells assessed as reduction of EGF-induced ERK1/2 activation at 40 uM after 60 mins relative to control

Basic Information

Activity Charts

Compound Summary