Basic Information
ID: ALA3611870
Type: Binding
Description: Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid beta 42 production by electrochemiluminescent assay
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA3611870
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 514.48 | 4.67 | 4.67 |
| 545.56 | 5.92 | 5.92 |
| 525.51 | 5.55 | 5.55 |
| 500.46 | 4.36 | 4.36 |
| 528.51 | 4.98 | 4.98 |
| 484.46 | 4.66 | 4.66 |
| 582.48 | 5.60 | 5.60 |
| 502.45 | 4.80 | 4.80 |
| 532.47 | 4.81 | 4.81 |
| 532.47 | 4.81 | 4.81 |
| 485.45 | 4.06 | 4.06 |
| 515.47 | 4.06 | 4.06 |
| 491.47 | 4.12 | 4.12 |
| 514.48 | 4.58 | 4.58 |
| 514.48 | 4.67 | 4.67 |
| 516.46 | 4.53 | 4.53 |
| 443.40 | 3.60 | 3.60 |
| 514.48 | 4.67 | 4.67 |
| 514.48 | 4.67 | 4.67 |
| 568.45 | 5.38 | 5.38 |
| 514.48 | 4.67 | 4.67 |
| 567.47 | 6.27 | 6.27 |
| 502.45 | 4.80 | 4.80 |
| 532.47 | 4.81 | 4.81 |
| 509.47 | 4.53 | 4.53 |
| 486.43 | 3.45 | 3.45 |
| 516.46 | 3.46 | 3.46 |
| 515.47 | 4.06 | 4.06 |