Basic Information
ID: ALA3614423
Type: Functional
Description: In-vivo inhibition of MGAT3-mediated TAG synthesis in human MGAT3 transgenic mouse assessed as reduction in incorporation of glycerol-d8 in to triolein expressed as atom percent excess at 200 mg/kg, po dosed 1 hr before of 100 mg/kg, iv glycerol-d8 and measured 30 mins post glycerol-d8 dosing and co-treated with 30 mg/kg for DGAT1 inhibitor-12 and 10 mg/kg for DGAT2 inhibitor-13 by LC-MS method
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA3614423
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 467.55 | 2.90 | 2.90 |