Basic Information
ID: ALA3614444
Type: Binding
Description: Inhibition of MRP1 (unknown origin)-mediated calcein-AM efflux expressed in HEK293/MRP1 cells at 0.5 uM after 1 hr by flow cytometry
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293/MRP1
Target: Multidrug resistance-associated protein 1(ALA3004)
Document: ALA3611986
Inhibition of MRP1 (unknown origin)-mediated calcein-AM efflux expressed in HEK293/MRP1 cells at 0.5 uM after 1 hr by flow cytometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3614444
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 525.61 | 5.40 | 5.40 |
| 646.74 | 6.37 | 6.37 |
| 586.69 | 6.36 | 6.36 |
| 627.81 | 6.66 | 6.66 |
| 687.86 | 6.67 | 6.67 |
| 601.73 | 5.37 | 5.37 |
| 585.73 | 5.67 | 5.67 |
| 640.59 | 6.66 | 6.66 |
| 589.69 | 5.50 | 5.50 |
| 589.69 | 5.50 | 5.50 |
| 639.70 | 6.38 | 6.38 |
| 537.68 | 4.71 | 4.71 |
| 664.83 | 6.58 | 6.58 |
| 869.65 | 7.67 | 7.67 |
| 628.75 | 5.32 | 5.32 |
| 639.70 | 6.38 | 6.38 |
| 613.78 | 6.28 | 6.28 |
| 711.86 | 6.14 | 6.14 |
| 699.75 | 6.39 | 6.39 |
| 645.78 | 5.68 | 5.68 |
| 653.78 | 7.92 | 7.92 |
| 613.84 | 8.42 | 8.42 |
| 561.68 | 6.21 | 6.21 |
| 598.63 | 5.86 | 5.86 |