Basic Information
ID: ALA3614558
Type: Binding
Description: Inhibition of N-terminal thioredoxin His6-tagged full-length human menin expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in menin interaction with FITC-MBM1 peptide of MLL (4 to 15 residues) by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3614558
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.51 | 3.80 | 3.80 |
| 454.43 | 3.99 | 3.99 |
| 400.45 | 3.28 | 3.28 |
| 418.45 | 3.44 | 3.44 |
| 436.44 | 3.91 | 3.91 |
| 361.54 | 3.26 | 3.26 |
| 379.53 | 3.21 | 3.21 |
| 397.52 | 3.50 | 3.50 |
| 451.49 | 4.35 | 4.35 |