Basic Information
ID: ALA3614582
Type: Binding
Description: Inhibition of recombinant human DAAO expressed in HEK cells using D-serine as substrate assessed as formation of alpha-keto acid, ammonia, hydrogen peroxidase after 20 mins by horseradish peroxidase/o-phenylenediamine-based assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: D-amino-acid oxidase(ALA5485)
Document: ALA3612020
Inhibition of recombinant human DAAO expressed in HEK cells using D-serine as substrate assessed as formation of alpha-keto acid, ammonia, hydrogen peroxidase after 20 mins by horseradish peroxidase/o-phenylenediamine-based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3614582
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 143.10 | -1.83 | -1.83 |
| 199.21 | -0.32 | -0.32 |
| 213.24 | 0.07 | 0.07 |
| 205.17 | -0.37 | -0.37 |
| 219.20 | -0.31 | -0.31 |
| 233.23 | -0.12 | -0.12 |
| 247.25 | 0.27 | 0.27 |
| 269.26 | 0.84 | 0.84 |
| 269.26 | 0.84 | 0.84 |
| 283.29 | 1.03 | 1.03 |
| 234.22 | -0.73 | -0.73 |
| 223.19 | -1.47 | -1.47 |
| 273.25 | -0.31 | -0.31 |
| 273.25 | -0.31 | -0.31 |
| 267.67 | 0.53 | 0.53 |
| 267.67 | 0.53 | 0.53 |
| 267.67 | 0.53 | 0.53 |
| 251.22 | 0.02 | 0.02 |
| 251.22 | 0.02 | 0.02 |
| 251.22 | 0.02 | 0.02 |
| 247.25 | 0.19 | 0.19 |
| 247.25 | 0.19 | 0.19 |
| 247.25 | 0.19 | 0.19 |
| 301.22 | 0.90 | 0.90 |
| 301.22 | 0.90 | 0.90 |
| 263.25 | -0.11 | -0.11 |
| 263.25 | -0.11 | -0.11 |
| 263.25 | -0.11 | -0.11 |
| 249.23 | -0.41 | -0.41 |
| 249.23 | -0.41 | -0.41 |
| 249.23 | -0.41 | -0.41 |
| 325.32 | 1.67 | 1.67 |
| 325.32 | 1.67 | 1.67 |
| 309.33 | 1.55 | 1.55 |
| 247.25 | 0.44 | 0.44 |
| 269.21 | 0.43 | 0.43 |
| 247.21 | -0.48 | -0.48 |
| 249.23 | -0.63 | -0.63 |
| 249.29 | 1.25 | 1.25 |
| 232.24 | 0.48 | 0.48 |